Cellular encapsulation is an advanced method for the implantation of living cellular systems to provide unlimited drug delivery. Cellular encapsulation is used for major applications, including the immobilization of allogeneic or xenogeneic cells in semipermeable membranes and immune protective membranes to deliver biological products to patients without the need of immunosuppression, and for treating secretory cell dysfunction. Cellular encapsulation obviates the need for surgical procedures, reduces the burden of cell sourcing, and provides target drug delivery.
The cellular encapsulation technique is used where the transplanted cells are protected from tissue rejection by enveloping the cells artificially, such as cell grafting. Delivering the therapeutic molecules across the blood brain barrier to the brain parenchyma is too difficult, and for resolving this issue, cellular encapsulation delivers the therapeutic molecules directly to the brain. A majority of the companies involved in cellular encapsulation are bringing in new technologies and advanced tissue engineering techniques to yield a well-established chemistry.
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Cellular encapsulation, on a broad category, includes microencapsulation and macro encapsulation, and these are the generally used types of cellular encapsulation in alginate hydrogels. The end user segments of cellular encapsulation include research centers and institutes, diagnostic laboratories, and pharmaceutical and biotechnology companies.
Cellular Encapsulation Market: Drivers and Restraints
The increased use of cellular encapsulation for the controlled delivery of biological therapeutics is expected to drive revenue generation in the global cellular encapsulation market. There is increasing demand for cellular encapsulation in new applications for emerging fields such as tissue engineering. The cellular encapsulation method is being used for future developments, which includes developing artificial organs by a combination of 3D material and cell complexes, use of stem cells for drug delivery, delivery of enzymes, and tissue integration. Cellular encapsulation provides different therapeutic strategies for regenerative medicine, along with growing applications in tissue engineering, which are other important factors that are contributing to the growth of global cellular encapsulation market.
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The increasing number of incidences of various types of cancers, such as pancreatic cancer, breast cancer, and brain tumor, and high prevalence of diabetes are expected to push the growth of cellular encapsulation technology to develop treatments for cancer and diabetes, and this is fuelling the growth of the global cellular encapsulation technology market. However, scientific development, ethical obstacles, government regulations, and market forces are expected to restrain the growth of the global cellular encapsulation market.
Cellular Encapsulation Market: Segmentation
The global cellular encapsulation market can be segmented on the basis of technique, material, application, and end user.
Based on technique and method, the global cellular encapsulation market is segmented as:
- Microencapsulation
- Simple Dripping
- Electrostatic Dripping
- Coaxial Airflow
- Liquid Jet Break Up
- Vibrating Jet Technique
- Jet Cutting Technique
- Spinning Disk Atomization
- Macroencapsulation
- Diffusion Chambers
- Ultrafiltration Membranes
- Cell Loading Chambers
- Immobilization Matrices
- Cell Engineering
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Based on material (polymer), the global cellular encapsulation market is segmented as:
- Alginate
- HEMA-MMA
- Chitosan
- Hydrogels
- Siliceous Encapsulates
- Cellulose Sulphate
- PAN-PVC
Based on application, the global cellular encapsulation market is segmented as:
- Biotechnology
- Healthcare
- Research
- Agriculture
- Cosmetics
- Environmental
Based on end user, the global cellular encapsulation market is segmented as:
- Academic Research Centers and Institutes
- Diagnostic Laboratories
- Pharmaceutical and Biotechnology Companies
- Others
Cellular Encapsulation Market: Key Players
The global cellular encapsulation market registers the presence of a large number of domestic manufacturers. Examples of some of the key players operating in the market are Austrianova Singapore Pte Ltd, Beta-Cell NV, Eli Lilly and Sigilon, Novo Nordisk, Semma Therapeutics, evotec, Living Cell Technologies Limited, Neurotech Pharmaceuticals, Inc., NovaMatrix, PharmaCyte Biotech, Inc., Sigma-Aldrich Co. LLC., and ViaCyte, Inc., among others.
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