Congenital Adrenal Hyperplasia Market: Introduction
- Congenital adrenal hyperplasia refers to a group of genetic conditions that affect the adrenal glands leading to low levels of cortisol and high levels of male hormones called androgens, causing development of male characteristics in females, and early puberty in both boys and girls. The milder and more common form of congenital adrenal hyperplasia (CAH) is called non-classic. The classic form, which is more severe, can be detected through newborn screening. Some forms of CAH can cause problems with normal growth and development in children and even be life-threatening.
- The global incidence of congenital adrenal hyperplasia in newborns is roughly 1 in 16,000 to 1 in 20,000 population. The incidence in the U.S. is around 1 in 16,000 to 1 in 18,000 population.
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Key Drivers and Restraints of Global Congenital Adrenal Hyperplasia Market
Government funding and support along with collaborative research with large pharmaceutical players is anticipated to boost the growth of the global market in the near future. In 2018, the International fund Raising for Congenital Adrenal Hyperplasia (IFCAH) launched eighth call for proposals, in association with ESPE.
Classic Segment to Dominate Global Market
- In terms of type, the classic segment accounted for major market share in 2018. The segment is expected to grow at a steady pace during the forecast period. It is likely to be driven by rise in prevalence of classic congenital adrenal hyperplasia across the globe. Classic congenital adrenal hyperplasia is the most prevalent form of congenital adrenal hyperplasia due to 21-hydroxylase deficiency, which is responsible for roughly 95% of cases. Classic congenital adrenal hyperplasia is of two types: simple virilizing and salt wasting. Salt wasting form of congenital adrenal hyperplasia leads to symptoms such as dehydration and hypotension in the first few weeks of life and can be life-threatening. The salt wasting congenital adrenal hyperplasia accounts for 70% of the classic congenital adrenal hyperplasia cases.
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Hospitals to Lead Global Congenital Adrenal Hyperplasia Market
- The hospitals segment is likely to capture nearly half of the market share in terms of revenue by 2027. It is projected to be the most lucrative segment of the global congenital adrenal hyperplasia market during the forecast period. Governments are extending support and funding toward increasing the number of skilled surgeons. This in turn increases the number of hospitals offering surgeries and treatment for congenital adrenal hyperplasia. For instance, the International Fund Congenital Adrenal Hyperplasia (IFCAH) is a private fundraising organization that aims to promote academic research on congenital adrenal hyperplasia.
- Well-established hospitals and health care infrastructure are anticipated to cater to the rise in demand for congenital adrenal hyperplasia treatment in North America during the forecast period. Developed countries are considered hubs for safe and effective surgeries. This perception will create opportunities in the congenital adrenal hyperplasia market in North America, followed by Europe. However, developing countries could present significant opportunities for investments and expansion for market players.
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- Asia Pacific is expected to be a potential market for congenital adrenal hyperplasia due to large patient pool and dense population. Growing medical tourism driven by government regulations favoring local players and relatively low surgery costs are likely to contribute to the lucrativeness of the congenital adrenal hyperplasia market in the region.
- However, high cost continues to hamper the growth of the congenital adrenal hyperplasia market in developed as well as developing countries. Financial lucidity of consumers has made them independent enough to spend out-of-the-pocket on their health. However, cost of these surgeries and treatments is high even after an insurance cover, which is preventing the market from realizing its full potential.
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Key Players Operating in Global Congenital Adrenal Hyperplasia Market
Pharmaceutical companies in the global congenital adrenal hyperplasia market are increasingly investing in the research & development on congenital adrenal hyperplasia drugs.
The global congenital adrenal hyperplasia market is moderately fragmented. Market players focus on strategic partnerships, collaborations, mergers, acquisitions, and product launches to increase market share. Leading companies operating in the global market are:
- Emerge Health
- Sentia Medical Sciences, Inc.
- Neurocrine Biosciences, Inc.
- Millendo Therapeutics, Inc.
- Spruce Biosciences, Inc.
- Thermo Fisher Scientific ( Life Technologies Corporation)
- Adrenas Therapeutics, Inc.
- Alder Biopharmaceuticals, Inc.
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