Global Bile Acid Sequestrate Drugs Market: Introduction
Bile acid sequestrant disrupts the enterohepatic circulation of bile acid by combining with bile components. It reduces plasma low-density lipoprotein cholesterol level, which in turn minimizes lipoprotein cholesterol level. Therefore, bile acid sequestrant is also called hypolipidemic agent. Bile acid sequestrant is commonly used as additive agent or second line therapy to treat hypercholesterolemia. It also helps in preventing reabsorption from gut, as it increases the excretion of bile acid in the stool.
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Key Drivers of Global Bile Acid Sequestrate Drugs Market
Rise in Prevalence of Lung Injuries, Lung Tumors, Congestive Heart Failure and Lymph or Blood Vessels Blockages
According to the Journal of Aerosol Medicine and Pulmonary Drug Delivery, acute Lung injuries has a high incidence (200,000 per year in the US) and overall mortality remains high.
According to the World Health Organization, lung is an internal organ most vulnerable to infection and injury from the external environment because of its constant exposure to particles, chemicals, and infectious organisms in ambient air. Globally, at least 2 billion people are exposed to the toxic smoke of biomass fuel, typically burned inefficiently in poorly ventilated indoor stoves or fireplaces. The most common lethal neoplasm in the world is lung cancer, which kills 1.6 million people each year and the number is increasing. According to the World Heart Federation, the global prevalence of heart failure has increased to an estimated 26 million, with millions of undiagnosed cases.
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Rise in Prevalence of Pleural Effusion
According to Journal of the Nigeria Medical Association, the incidence of pleural effusion in the U.S. is estimated to be at least 1.5 million cases annually. The most common symptom of pleural effusion is dyspnea. According to StatPearls Publishing LLC, pleural effusion is the most common disease among all the pleural diseases and affects 1.5 million patients per year in the U.S.
North America to Account for Major Share of Global Bile Acid Sequestrate Drugs Market
North America is projected to account for major share of the global bile acid sequestrate drugs market during the forecast period. This is attributed to increase in incidence of heart disorders in the region. High consumption of unhealthy and acidic food fuels demand for bile acid sequestrate drugs in the region. Large geriatric population and rise in awareness about the effect of high cholesterol in the body boosts the demand for bile acid sequestrant drugs in Europe. Asia Pacific is expected to capture significant share of the global bile acid sequestrant drugs market in the next few years. Increase in consumption of junk food and rise in number of diabetic patients in countries such as China and Japan are likely to drive the market in the region.
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Key Players Operating in Global Bile Acid Sequestrate Drugs Market
The global bile acid sequestrate drugs market is highly consolidated owing to the presence of small number of key players. Leading players operating in the global bile acid sequestrate drugs market are:
- Daiichi Sankyo Company Limited
- Upsher-Smith Laboratories, LLC
- Pfizer, Inc.
- Sandoz, Inc.
- Endo Pharmaceuticals, Inc.
- AstraZeneca
- Merck
- Amgen
- Sanofi Esperion Therapeutics
- CJ Healthcare
- Crestor
- Zetia
- Vytorin
- Welchol
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