Precautionary Measures for Pets during COVID-19 Pandemic Fuels Demand for Isoxazoline Drugs
The COVID-19 (coronavirus) pandemic-related mobility issues have led to pet owners stocking up on consumables and medications for their cats and dogs. Companies in the U.S. Isoxazoline market have strengthened their supply chains to tide over uncertainties in demand. According to latest veterinary news, the FDA (Food and Drug Administration) has approved a novel combination Isoxazoline parasite preventive for dogs in the U.S. This has created incremental opportunities for manufacturers in the U.S. Isoxazoline market.
Pharma companies are experiencing a decline in the demand for drugs and topical medications for pets. However, concerned pet owners are ensuring steady supply of drugs and medications from their insurance companies and suppliers. The awareness about standard precautionary measures for pets during the ongoing COVID-19 pandemic has fueled the demand for drugs and medications.
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Isoxazolines or Imidacloprid-Moxidectin Combination: Which is More Effective in Treatment of Red Mange?
There is a high prevalence of generalized demodicosis or red mange in dogs. Ongoing investigations in Isoxazoline and a combination of imidacloprid and moxidectin are being debated in the field of parasitology. It has been found that Isoxazolines have a comparable efficacy over combination of imidacloprid and moxidectin. Fluralaner, sarolaner, and afoxolaner hold promising potentials in the treatment of generalized demodicosis in dogs. As such, afoxolaner is not only projected to hold a lion’s share, in terms of value, but its products are anticipated for exponential growth during the assessment period in the U.S. Isoxazoline market.
Companies in the U.S. Isoxazoline market are streamlining their production activities as per changing dosage frequencies for dogs. The severity of red mange among dogs is laying the basis for drug manufacturing.
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Drug Resistance Leads to Investments in Resistance-breaking Antiparasitics with New Modes of Action
The U.S. Isoxazoline market is predicted to expand at a favorable CAGR of ~14% during the forecast period. However, many pet owners are encountering drug resistance issues in their cats and dogs. This has triggered the need for novel resistance-breaking antiparasitics with new mechanisms/modes of action. Pharma companies must invest in new modalities pertaining to parasitic vaccines or environment-friendly interventions to increase the availability of efficacious treatments. Companies in the U.S. Isoxazoline market are increasing their R&D in oxime-participating cyclization strategy for the construction of efficacious compounds.
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Innovations with Oral Formulations for Sarolaner Prove Efficacious in Treatment of Ticks and Fleas
Apart from fluralaner and afoxolaner, companies in the U.S. Isoxazoline market are increasing their focus in sarolaner, which is found to be highly effective against ticks and fleas in dogs. Once a month administration of sarolaner is being recommended by veterinarians. The FDA approval of sarolaner is encouraging manufacturers in the U.S. Isoxazoline market to innovate in new drug formulations and topical solutions. For instance, Zoetis— one of the key producers of medicine and vaccinations for pets and livestock is gaining market recognition for developing sarolaner from azetidine-based Isoxazoline lead.
Pharma companies are increasing their production capacities in oral formulations for sarolaner, since topical formulations are typically washed off or licked off by dogs.
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