Nucleic acids are one of several macromolecules found in the body in addition to fats, proteins, and carbohydrates. A nucleic acid is a polymer composed of four nucleotides linked together in a long chain known as polynucleotide. A nucleic acid consists of DNA, RNA, and protein.
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The extraction and purging of nucleic acids are regularly utilized strategies to isolate genetic material from tissues, microscopic organisms, plants, and infections for imperative, explanatory, indicative, and preparative downstream procedures. Among these techniques, plasmid DNA extraction was the first to be recorded to have utilized the tedious alkaline extraction protocol.
Generally, successful refining of nucleic acids involves four important steps viz. effective disruption of cells or tissues, denaturation of nucleoprotein complexes, inactivation of nucleases (for example, RNase for RNA extraction and DNase for DNA extraction), and decontamination. The recent point-of-care diagnostics (POC-Dx) is a new approach aimed at replacement of sophisticated analytical machinery with micro-analytical systems, and able to be used near the patient, at the point of care or point of need.
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Based on chemical, the nucleic acid extraction reagents market has been segmented into proteinase K, NaCl, CTAB/NaCl solution, chloroform/isoamyl alcohol 24:1, phenol/chloroform/isoamyl alcohol 25:24:1, isopropanol, and ethanol. Ethanol and phenol segments are expanding at a high rate, as the two reagents are easily available, price-compatible, and highly effective.
Based on end-user, the nucleic acid extraction reagents market can be classified into academic research institutes, hospitals & diagnostic centers, pharmaceutical & biotechnology companies, contract research organizations (CROs), and others (such as food testing and forensic laboratories). The academic research institutes segment holds a leading share of the global market, while the hospitals & diagnostic centers segment is likely to expand at the maximum growth rate during the forecast period.
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This growth is attributable to the increasing use of nucleic acid tests in molecular diagnostics. The importance of pure nucleic acid for applications in industries such as pharmaceutical and biotechnological has filled its request in the examination and life science markets. The confinement of nucleic corrosive in the pure shape is required for medicate disclosure, sub-atomic diagnostics, and genotypic applications.
The mechanical developments and progressions; and government activities in type of subsidizing for investigate ventures are the elements driving this market. Besides, the expanding utilization of nucleic corrosive based tests in conclusion is relied upon to drive this market in coming future. However, expending market consolidation and low penetration of automated nucleic acid isolation and sanitization techniques in emerging economies are the major factors hindering the growth of this market.
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Geographically, the global nucleic acid extraction reagents market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America and Europe cumulatively held a major share of the global market, due to rapid economic development and increase in health care expenditure in these regions.
However, countries in Asia Pacific such as India, China, and Japan offer immense growth opportunities for the market, due to increasing R&D expenditure and technological advancements in these countries. In Middle East & Africa countries the development of the healthcare project and economy help to increase the market of the nucleic acid extraction reagent.
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Key players operating in the global market for nucleic acid extraction reagents are Agilent Technologies Inc., Bio-Rad Laboratories, Inc., Danaher Corporation, F. Hoffmann-La Roche AG, General Electric Company, Qiagen N.V., Sigma-Aldrich Co. LLC, Takara Bio, Inc., and Thermo Fisher Scientific, Inc.
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