The global Peptide Therapeutics market was valued at USD 25.35 billion in 2018 and is expected to reach USD 50.60 billion by the year 2026, at a CAGR of 9.0%. Peptide drugs are used as replacement therapies which supplements peptide hormones when the endogenous levels tend to decrease. The first peptide therapeutic was used to treat diabetic patients in the 19th century. The approval for 60 peptides has been granted, with the clinical global administration in the United States, Europe, and Japan. These drugs are used as drug target moiety for cancer, metabolic disorders, cardiovascular disease.
To improve efficiency, conjugates became a boon to alter the properties of proteins. The Polyethylene Glycol (PEG) conjugation, lipids, and proteins have been used for extending the half-life. In recent years, cell-penetrating peptides, termed as ideal transporters, are responsible for assisting the therapeutic cargos in a non-toxic and simple manner being protein, oligonucleotides, nanoparticles. They are currently used in cancer therapy due to its potent and quick delivery.
Specific problems and restraints are shown by peptide therapeutics. The drawbacks are short plasma life and the inability of the functioning of oral bioavailability. By increasing the drug stability and peptide formulation, the peptide therapeutics can be taken in an oral form quickly.
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Further key findings from the report suggest
- The peptide therapeutics market is expected to reach USD 50.59 billion by the year 2026 at a CAGR of 9.0%, according to the forecast period.
- Kallyope, a U.S based company, and Novo Nordisk, a Denmark based Company, entered into a research collaboration and agreement to discover novel therapeutics for treating obesity and diabetes in June 2018.
- North America has the largest market share of 38.2% in the year 2018. Its increased dominance in the market is due to the increased investments of Research and Development, high incidence of cancer, and increased demand for healthcare expenditure. The advent of Peptide conjugates will also further drive a rapid increase in the market.
- The solid-phase peptide synthesis is expected to reach USD 22.6 billion by the year 2026, showing a good growth market in the year 2026.
- Hybrid technology is expected to grow with a CAGR of 8.8% in 2026.
- Asia Pacific is hyped to be the largest growing market with a CAGR of 10.2%, with USD 10.51 billion in the forecast period due to high untapped opportunities, affordable cost of raw material, and increasing base of companies providing outsourcing services, flourishing biotech industry, and increasing investments in Research and Development sector. Patent expiration of blockbuster drugs would foster generic market, thus expected to provide significant growth opportunities shortly.
- The Cancer type application segment held the largest market share of 37.3% in 2018. Increased occurrence of cancer worldwide and the growing treatment of cancer treatment are the key factors responsible for dominance in this segment.
- The Metabolic diseases segment has shown immense market size growth of USD 7.05 billion in 2018 and will show a significant market growth of 8.9% according to the forecast period due to Cumulative acceptance of inactive lifestyle, unhealthy food habits, and consumption of a high amount of alcohol has led to increased occurrence of these disorders.
- In May 2018, Bicycle Therapeutics, a biotechnology company showcased a new class of therapeutics based on its proprietary bicyclic peptide (Bicycle) product platform, announced that it is expanding its collaboration with AstraZeneca to include additional targets in respiratory and cardio-metabolic diseases. AstraZeneca is accountable for further development and product commercialization.
- PeptiDream, a Japanese biotechnology company, had declared a new peptide drug conjugate (PDC) collaboration with Swiss pharma major Novartis in June 2019. PeptiDream will use its proprietary Discovery Platform System technology to identify unique macrocyclic and constrained peptides, as PDCs against numerous targets of interest, chosen by Novartis.
- Computational Biology and screening have good chances of improvement to support drug delivery.
- On January 2019, a peptide was received by Leidos Health Life Sciences, for a novel PD-1 checkpoint inhibitor
Key companies operating in the market include:
Sanofi (Australia), Teva Inc (Israel), Novo Nordisk Inc, (Denmark), Takeda (Japan), Eli Lily (United States), Astra Zeneca (U.K.), Novartis (Switzerland), Shire (U.S.) Abbvie (U.S.), Ipsen (France) Allergen (Ireland ), Ferring (Switzerland), Merck (United States), The Medicines (United States), Roche (Switzerland) Johnson and Johnson (United States).
The report covers an extensive analysis of the key market players in the market along with their business overview, expansion plans, and strategies. The report also focuses on recent strategic alliances in the market including mergers and acquisitions, joint ventures, partnerships, agreements, corporate and government deals, product launches, and brand promotions, among others.
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The report aims to provide a better understanding of the market dynamics and the workings of the industry on a global level. To gain a deeper understanding of the industry, the global Peptide Therapeutics market is further segmented on the basis of key geographical regions such as North America, Latin America, Europe, Asia-Pacific, and the Middle East & Africa. The report also offers a country-wise analysis to provide crucial insights into market size, market growth, market revenue growth, and economic growth in each region.
On basis of product types and application offered by the Peptide Therapeutics industry, the market is segmented into:
Route of Administration (Revenue in Million USD; 2016–2026)
- Parenteral Route
- Oral Route
- Pulmonary
- Mucosal
- Others
Product Type Outlook (Revenue in Million USD; 2016–2026)
- Generic
- Innovative
Type of Manufacturers (Revenue in Million USD; 2016–2026)
- In-house
- Outsourced
Application Outlook (Revenue in Million USD; 2016–2026)
- Cancers
- Metabolic
- Cardiovascular Disorder
- Respiratory
- GIT
- Anti-infection
- Pain
- Dermatology
- CNS
- Renal
- Others
Synthesis Outlook (Revenue in Million USD; 2016–2026)
- Solid Phase Peptide Synthesis (SPPS)
- Liquid Phase Peptide Synthesis (LPPS)
- Hybrid Technology
The regional analysis covers:
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- U.K.
- Italy
- France
- BENELUX
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Rest of LATAM
- Middle East & Africa
- Saudi Arabia
- A.E.
- South Africa
- Rest of MEA
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Benefits of Peptide Therapeutics Market Report:
- Panoramic overview of the opportunities and risks in the Peptide Therapeutics sector
- Study of recent innovations and developments in the industry
- Comprehensive study of the growth pattern of the Peptide Therapeutics industry
- In-depth assessment of the competitive landscape of the key players of the Peptide Therapeutics industry
- Analysis of the Peptide Therapeutics market drivers, constraints, and opportunities
- Assessment of technological developments and latest trends of the industry
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